摘要：目的：通过对大鼠在静磁场和非磁场作用下其牙槽骨的内源性前列腺素E₂随时间变化的对比研究，了解在静磁场作用下，大鼠牙槽骨中前列腺素E₂含量的时间变化性。方法：放射免疫法检测20只加静磁场、20只加非磁场和4只空白对照的大鼠牙槽骨中前列腺素E₂的含量，探讨静磁场对大鼠牙槽骨的内源性前列腺素E₂的变化的影响。结果：未受力时，大鼠的牙槽骨内即存在一定数量的前列腺素E₂。在静磁场作用下，牙槽骨的内源性前列腺素E₂在1 h内即开始升高，在6 h时达高峰，随即开始下降，但速度缓慢，24 h时仍高于正常。加非磁场组前列腺素E₂的变化趋势同加磁场组，但前列腺素E₂开始反应慢，峰值却高于加磁场组。且12，24 h时的前列腺素E₂水平亦高于加静磁场组。结论，牙槽骨的内源性前列腺素E₂的变化与静磁场的生物学效应有关。

Changes of Prostaglandin E₂ Level in the Alveolar of Rats in Static Magnet Field

Chang Xin ,Qin Ke ,Lu Yong Li

(Department of Orthodontics, Stomatology Hospital, China Medical University, Shen Yang, 110002)

Abstract：This experiment studied the changes of prostaglandinE₂ lever in the alveolar of rats in static and non-magnetic fields in order to understand the changes of prostaglandin E₂ in the alveolar of rats with the time in static magnetic field. Methods :Radioimmunoassay was used to examine the level of prostaglandin E₂ in the alveolar of 20 rats in static magnetic field, 20 rats in non-magnetic field, and 4 control rats. Results:There is prostaglandin E₂ in the alveolar of rats under no influences. In static magnetic field the prostaglandin E₂ level in the alveolar began to rise within an hour, and arrived at its peak at 6 hours, then began to go down slowly, but still high at 24 hours as compared with the standard. As for the non-magnetic field group, the changing trend is same with the static magnetic field group although the starting speed is slow, the peak and the level of the 12 hours, 24 hours are also higher than the static magnetic field group. Conclusion:We think that this phenomenon is concerned with the biological effects of static magnetic field.

Keywords：prostaglandin E₂; static magnetic field; non-magnetic field; alveolar

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