摘要：层粘连蛋白和纤维粘连蛋白是细胞外基质的重要成分，在正常组织中有广泛分布。 目前认为层粘连蛋白有10条不同源的多肽链，构成11种不同的蛋白分子。纤维粘连蛋白的结构具有多形性，主要由ED-A、ED-B、Ⅲ CS三个结构区不同的拼接方式所决定。层粘连蛋白和纤维粘连蛋白不仅在支持、连接和维持组织形态，调节细胞的粘附、生长、分化、增殖等方面起重要作用，而且与胚泡着床及胎盘的形成也有密切关系。参考文献：

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