摘要：本文简要综述了内皮素对哺乳动物心肌的生理效应及作用机制，特别是着重从心肌力学、心肌收缩力、心肌动作电位及心肌超微结构等方面较为系统地阐明了适当剂量的内皮素对哺乳动物心肌活动的正性作用及较高剂量内皮素的负性影响，并用细胞内钙离子增加的理论对内皮素影响心肌活动的机制作了初步分析和探讨。参考文献：

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