The Study of the Clinical Curative Effects of Felodipine Extended-release Tablets

zeng Huanqong,Liu Xingbin,Rao Li,Zhang Qing,Huang He(The department of cardiology, the first hospltal of WCUMS Chengdu 610044)

Abstract：To study the hypotension action and the effects of ventricular diastole of extended-release felodipinetablets. Method: we employed a self-crossover study to learn 30 patients of hypertension with felodipine tablets 5mg once a day for 4 weeks, then analyzed the results statistically. Results: The systolic and the diastolic pressure of the patients decreased by 4.4 0.9kPa and 2.5 1.0kPa respectively, compared with those without using felodipine( P< 0.05). 50% of the patients was improved and 40% effective. The overall effective rate was 90%. Parameters of ventricular diastole: the Emax of the electrdiograms of the patients was increased by 7%, while the A, A/E and DT decreased by 13.2 %, 18.7 % and 17.4 % respectively, compared with those without using felodipine (P < 0.01 ).C0nclusion: felodipine can decrease the blood pressure and improve the diastolic functions of the heart ventricles.

Keywords：felodipine extended release tablet; hypertension; the diastolic functions of left ventricles作者单位：非洛地平缓释片对高血压病的疗效观察（华西医科大学附属第一医学院心内科 成都 610041）参考文献：

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